The role of exercise on the innate immunity of the elderly

The increased life span in human population has shown that some diseases, as infections, cancer and autoimmune phenomena, occur more frequently in the elderly than in the younger. We describe the ageing process involving the innate immune system and the improvement given by moderate physical activity. In addition, we discuss the altered neutrophil granulocytes function, the role of macrophages and natural killer cells, besides the influence of cytokines and secretory IgA. The acquired information help us to explain how these changes could favor the onset of diseases in the elderly and how they may boost their immune function.     

New algorithms for k-center and extensions

The problem of interest is covering a given point set with homothetic copies of several convex containers C ₁,…,C _k , while the objective is to minimize the maximum over the dilatation factors. Such k-containment problems arise in various applications, e.g. in facility location, shape fitting, data classification or clustering. So far most attention has been paid to the special case of the Euclidean k-center problem, where all containers C _i are Euclidean unit balls. Recent developments based on so-called core-sets enable not only better theoretical bounds in the running time of approximation algorithms but also improvements in practically solvable input sizes. Here, we present some new geometric inequalities and a Mixed-Integer-Convex-Programming formulation. Both are used in a very effective branch-and-bound routine which not only improves on best known running times in the Euclidean case but also handles general and even different containers among the C _i .     

Young urban adults' heterosexual risk encounters and perceived risk and safety: a structured diary study

Using diary methods, the current study explored characteristics of young adults' sexual risk interactions over a two-week period and the associations between perceived risk and safety with regard to these sexual risk behaviors. We screened all participants to ensure a moderate to high scores on an HIV knowledge measure. Men (n = 44) and women ( n = 48) enrolled at an inner-city college collected diary data, generating reports of 440 sexual occasions over a 2-week period (1,278 person-days). Despite participation in sexual risk activities, including highly inconsistent condom use during intercourse, participants uniformly reported high safety and little to no risk. Only women's perceptions of safety (not risk) were associated with condom use, men's perceptions of both safety and risk were unrelated. Ratings of safety and risk appeared to operate independently for the most part. Sex with new partners and new sexual activity were associated with both judgments of greater risk and lower safety were associated for men only. These results add to the growing evidence that young people fail to integrate fully their general knowledge regarding HIV risk into their personal interactions. This study has implications for the development of cognitive models around sexual decision-making for young adults at risk for HIV and may provide insight into the contextual features of sexual interactions associated with young people's perceptions of risk and safety.     

Talking about Beauty: A Study of Everyday Aesthetics among Low‐Income Citizens of Milan

This paper reports on research undertaken into the aesthetics of the everyday. As well as the subject matter of aesthetic philosophy, art criticism and of the sociology of art, beauty, and beautiful are of course very ordinary matters too. To shed light on the meanings of beauty as used in everyday settings and in natural language, we use the data collected in a study conducted with a group of low‐income residents of the city of Milan. In this study we were interested in analyzing their lifestyle in terms of their relationship with aesthetics, i.e., with “beautiful” objects and/or experiences. Participants' self‐reported aesthetic appreciations suggest that conceptions of “beauty” are used as devices to narrate pieces of identity, memories, experiences, etc. Their aesthetic judgements take on an anthropological function, creating a framework of meanings that help the participants make sense of the world of objects and of their own lives with/through them.     

Fertility treatment and organizational discourses of the non-reproductive female body

This paper contributes to debates on the intersections between organizations, the body, and reproduction by exploring how the non-reproductive female body is discursively (re)constructed by organizations which provide fertility treatment, such as private clinics and fertility magazines. Organization studies has neglected the non-reproductive body, despite a fair amount of research on its reproductive counterpart, especially pregnant and maternal bodies. Equally, these discussions privilege the employment relationship – for example, how women are enjoined to manage their bodies at work – whereas we concentrate on the marketplace, or the field of fertility treatment, and the organizations therein. These organizations, while focused on reproducing bodies, also influence, compound, and challenge notions of the bodies they are involved with. Through a Critical Discourse Analysis of texts produced by UK fertility organizations, we present three discourses of the non-reproductive female body that (re)generate subject positions where the absence of reproduction is a medical condition, an emotionally distressing experience, and something that needs to be cared for. Our argument suggests how the texts can operate as a form of Foucauldian governmental biopower, emphasizing how they hail the infertile female subject.     

Influence analysis in skew-Birnbaum–Saunders regression models and applications

In this paper, we propose a method to assess influence in skew-Birnbaum–Saunders regression models, which are an extension based on the skew-normal distribution of the usual Birnbaum–Saunders (BS) regression model. An interesting characteristic that the new regression model has is the capacity of predicting extreme percentiles, which is not possible with the BS model. In addition, since the observed likelihood function associated with the new regression model is more complex than that from the usual model, we facilitate the parameter estimation using a type-EM algorithm. Moreover, we employ influence diagnostic tools that considers this algorithm. Finally, a numerical illustration includes a brief simulation study and an analysis of real data in order to show the proposed methodology.     

Integrating strategic planning and performance management in universities: a multiple case-study analysis

Journal of Management and Governance - Over time, public universities have been involved in a process of modernisation based on a new concept of governance and managerial methods for increasing...     

Digital internal communication: An interplay of socio-technical elements

Digital transformation has become a research focus in recent years. Likewise, internal communication (IC) is one of the fastest-growing specialisations in public relations and communication management. This research explores digital internal communication (DIC) at the nexus between digital transformation and IC. We provide an integrative review of the literature; our thematic analysis of selected journal articles and other scholarly texts is guided by the concept of organisations as socio-technical systems. Furthermore, we create a template using NVivo software to organise the emerging themes and clusters following the logic of communication levels. This template allows us to explain the phenomenon of DIC in a socio-technical organisational system and discuss how the emerging themes are interrelated, people-focused, and linked to competency development and trust-building. As a contribution to theory, we offer a conceptual model which illustrates the dynamics of DIC as an interplay of socio-technical elements on three communication levels. This conceptual model can be further developed in scholarly discussions on DIC and by organisations reflecting on their IC use in a digital workplace environment.